Thursday, October 25, 2012

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How To Play Electric Blues Guitar (Bk/Cd)- U.K., by Alan Warner

(Music Sales America). A comprehensive guide to electric blues guitar playing, this fast-paced method covers all aspects of modern and traditional electric blues guitar. It contains over 90 musical examples in standard music notation and tablature, along with playing and performance tips. The full-length CD includes demonstrations, exercises, and play-along backing tracks.

  • Sales Rank: #3193827 in Books
  • Brand: Warner, Alan
  • Published on: 2000-01-01
  • Released on: 2000-01-01
  • Original language: English
  • Number of items: 1
  • Dimensions: 12.00" h x .20" w x 9.00" l, .63 pounds
  • Binding: Paperback
  • 64 pages

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0 of 1 people found the following review helpful.
Five Stars
By Eric Beck
good

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Thursday, October 18, 2012

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  • Sales Rank: #5694573 in Books
  • Published on: 1900
  • Binding: Paperback

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Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature’s only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds―those derived from the plant Mitragyna speciosa. This plant, known as Kratom in Thailand or Biak-Biak in Malaysia, has long been used locally as treatment for pain, fever reduction, diarrhea, and even depression.

Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source presents an introduction to the chemical and biological properties of alkaloids isolated from M. speciosa as well as their synthetic analogs. The book covers various topics including phytochemistry, medicinal chemistry, and pharmacology. Current research, analgesic effects, and addiction potential are also discussed. As the first extensive text on the basic science and clinical use of Kratom, the book provides readers with a concise yet comprehensive introduction to nature’s "other opioid."

  • Sales Rank: #1470910 in Books
  • Published on: 2014-10-29
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.20" h x .80" w x 6.20" l, .0 pounds
  • Binding: Hardcover
  • 366 pages

Review

"This is a novel foray into the realm of reviews on non-poppy-derived opioids and their pharmacology and … provides very solid information about the chemistry of the mitragynines…The editor, Robert Raffa, is a widely known expert in the pharmacology of opioid drugs with significant knowledge and respect in the field."
―Kenneth E. McCarson, BChE, PhD, University of Kansas Medical Center for Doody's Review Service

"This book should be an indispensable single-volume information source for anyone working in the fields of opioid chemistry, pharmacology and toxicology. Some chapters would be of particular interest to … specialists working in addiction treatment and drug regulation. The book would also be an excellent addition to any library collection specialized in natural products or drugs of abuse."
―Journal of Addition Research and Therapy

About the Author

Robert B. Raffa is a professor of pharmacology in the Department of Pharmaceutical Sciences at Temple University School of Pharmacy as well as a research professor in the Department of Pharmacology at Temple University School of Medicine. He has bachelor’s degrees in chemical engineering and in physiological psychology, master’s degrees in biomedical engineering and toxicology, and a doctorate in pharmacology. Dr. Raffa was co-leader for analgesics discovery at Johnson & Johnson and was pivotal in the elucidation of the mechanism of action and development of the analgesic drug tramadol (Ultram™). He is the co-holder of several patents, including the combination of tramadol plus acetaminophen (Ultracet™). He has published more than 280 scientific articles in peer-reviewd journals and is the co-author or editor of several books.

Most helpful customer reviews

25 of 25 people found the following review helpful.
Excellent Book. Needs to be Affordable.
By juki654
I've just read Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source, ed. by Robert B. Raffa. In the preface, Professor Raffa explains the book evolved from an elective course taught at Temple University School of Pharmacy, and is a collection of essays by experts in various fields (chemistry, biology, pharmaceutics, forensic toxicology, etc.).

First of all, this is a valuable book, and my only real criticism of it is that it is priced much too high. Perhaps the hardback needs to be so expensive, but why can’t the e-book be a reasonable price?

Also, I didn't have the background to understand all of the essays. I found myself looking up terms every couple of minutes while reading. Many of the essays are descriptions of the chemical and biological elements of kratom, and I pretty much skipped these, as they were very dense reading, and I was more concerned with the way kratom functioned as a drug.

Short Review:

Kratom has enough opioid properties that it should be classified as an opioid, albeit a new one. Kratom has significant pain-relieving properties. It also seems to suppress coughs, has some anti-depressive properties, and can produce euphoria at high doses. It does suppress breathing but less so than classic opioids. It also causes much less constipation. It seems to be less toxic than classic opioids, as there are no verified reports of it acting alone to cause deaths. There are anecdotal reports, and worry, that it can cause dependence and addiction. Most of the chapters call for more research to be done.

Notes from the Chapters I Read:

Chap 2

Makes the case that kratom can be classified as an opioid. Has two alkaloids—mitragynine (MG) and 7-hydroxymitragynine (7-OH-MG)—that show binding affinity for opioid receptors. Also shows pain relief, miosis (constriction of pupils), constipation, respiratory depression, and tolerance. Also, when an alkaloid is injected into mice, and then an opioid antagonist (blocks opioid action) is also injected, the mice show signs of opioid withdrawal.

A non-opioid property is that very high doses injected into rodents did not seem to poison them. No evidence of toxicity was found. In addition, the compounds in kratom “appear to produce less emesis (vomiting) and respiratory depression than does codeine, although much more detailed investigation is needed.”

The chapter concludes by asserting that “these alkaloids are a novel (or at least distinct) class of opioids. It appears that biodiversity has provided an alternative natural source of opioid compounds.”

Chapter 13

Points out that the pain-relieving effects of kratom cannot be explained by just the MG alkaloid, which is less potent than morphine. The 7-OH-MG alkaloid (small amount present in kratom) produces the strongest pain-relieving effect, maybe ten times stronger than morphine. The chapter urges more research into all of the alkaloids in kratom, concluding that “unknown ancient treasures are still hidden in the Thai traditional medicine M. speciosa, and we should hunt for them.”

Chapter 14

Compares the non-pain relieving aspects of kratom and other opioids

Both inhibit coughs. They were “equipotent.”

Both produce respiratory depression, but kratom’s effect is milder.

Euphoria: the authors note that kratom users report that a high dose of kratom is needed to produce euphoria and they speculate there is some compound in kratom that blocks euphoria at low doses.

Animals didn’t show as marked a preference for places where they received kratom, as they did for places where they got other opioids. Authors concluded the kratom extract used either did not have a sufficiently high concentration of active compounds, or that it contained some compound that blocked its effects.

They found some antidepressant activity in kratom.

Chapter 15

There is a discussion on opioid-induced constipation here. They found that morphine and the 7-OH-MG alkaloid in kratom slowed the travel of food through the large intestine to the same degree. However, since 7-OH-MG is ten times more potent than morphine for pain relief, you would need ten times less 7-OH-MG and therefore constipation would not be such a problem. When the MG alkaloid is compared to morphine and codeine as far as causing constipation, it was found that MG didn’t slow the food down nearly as much as morphine and codeine. So both of the pain-reducing elements in kratom cause less constipation than traditional opioids. The authors present this as a “possible clinical benefit, as opioids are commonly associated with constipation.”

Chapter 16

The authors quote fragments from postings by kratom users to a site called Erowid. Most of the quotes are from people trying to use kratom to detox from harsher opioids, or to feel euphoria, or to manage chronic pain. There was also some discussion of withdrawal symptoms. The authors also publish what they say is a “small number” of people who feel they may have caused themselves temporary liver or gall-bladder problems by using kratom.

Chapter 18

This is a long chapter detailing “adverse effects and toxicity” of opioids from the poppy plant—not kratom.

Chapter 19

This is on the “Toxicology of Mitragynine and Analogs.”

The chapter begins by pointing out that “To date, there have been no reports of fatal overdose of kratom per se. If there are such occurrences, they are probably the result of kratom products contaminated with synthetic adulterants.”

Most of the studies are with animals. One interesting thing found was that the Mitragynine content in the kratom extracts vary significantly by geographic origin. So the kratom in Thailand reported a higher mitragynine content than an extract from Malaysia.

The researchers tested the safety of MG by giving higher and higher doses to the rats. They concluded that it was only at the highest doses that any liver or kidney damage was found, and even then, “there were no significant effects of other biochemical parameters, such as cholesterol, triglycerides, total protein, creatinine, albumin, alkaline phosphates, or glucose levels.”

There don’t seem to have been any studies on humans but “despite informal and unsupervised widespread use of kratom, there are no reports of mortalities after ingestion of kratom alone, even after chronic and high-dosage consumption, but serious adverse reactions have been reported in several cases.” The cases referred to involve people who took adulterated kratom products, or mixed kratom with other substances. The chapter concludes by calling for more studies, so the “risk-benefit” equation for kratom can be more fully known.

One interesting point that came up in this chapter is that MG is a “poorly water-soluble drug . . . and has an acid-degradable nature.” That must be why it seems to dissolve in orange juice but not in water.

Chapter 20

This chapter is really looking ahead, to talk about what kinds of studies should be done. It recommends animal studies to see the abuse potential of the alkaloids in kratom. This chapter was very difficult to read, but I think it essentially said that pain-relieving properties have been established so now studies should focus on the dangers of the drug. It concludes that “many strides . . .have been made . . . regarding its potential therapeutic uses as an analgesic, anti-inflammatory agent, and muscle relaxant.” It also concludes that kratom can produce tolerance and physical dependence. It asks for studies “to assess the positive reinforcing and drug-seeking effects of mitragynine and drug discrimination assays to assess mechanistic similarities between mitragynine and prototypic drugs of abuse.”

Chapter 21

The author of this chapter, Professor Aziz Zoriah from the University of Malaya in Malayasia, gives the background of kratom. It was exclusive to Southeast Asia until around 1990, when the Internet made it easy to order. In Southeast Asia it is widely used, mostly as a stimulant to increase work production and treatment for opioid withdrawal symptoms. He cites a Malaysian study and a Thai study that both show a large percentage of the users reported they had trouble stopping. Professor Zoriah thinks this is because kratom is so easily available there, and so cheap, that users regularly take large doses. Along with all of the other researchers, he calls for more substantive research to be done on this drug.

Final Thoughts:

This is clearly a drug that needs to remain legal. It has many medical uses and has not caused one death yet—as opposed to alcohol, which new research shows causes an average of six deaths every day.

1 of 2 people found the following review helpful.
Fantastic.
By Casey Jones
The title says it all. I am working on a Ph.D. in a pharmacology-related field and wanted to write a research proposal on mitragynine. This book was an incredible investment for that purpose. It is somewhat specialized, although a determined average reader could reap plenty of benefit from it. Citations and references are thorough and extremely helpful. Great book, through and through.

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Tuesday, October 16, 2012

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  • Published on: 2013-11-08
  • Binding: Paperback

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Monday, October 15, 2012

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Growing Up with... The Jam, by Nicky Weller, Gary Crowley, Russell Reader, Den Davis

  • Sales Rank: #3388868 in Books
  • Published on: 2015-06-22
  • Original language: English
  • Dimensions: 13.46" h x .47" w x 9.53" l, 2.25 pounds
  • Binding: Paperback
  • 184 pages

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0 of 0 people found the following review helpful.
this is the modern world
By Linda Salecker
fantastic book if you love the jam and paul weller. does anyone NOT love paul weller?

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Sunday, October 14, 2012

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Effective Leadership and Management in Nursing (8th Edition) (Effective Leadership & Management in Nursing (Sull), by Eleanor J. Sullivan

Extensively updated to reflect the latest changes in the healthcare system, EFFECTIVE LEADERSHIP AND MANAGEMENT IN NURSING, 8/e will help both practicing and student nurses manage successfully in today’s challenging, resource-limited healthcare environments. The most up-to-date and complete learning package for nurses who intend to manage, this book combines practicality with conceptual understanding, tapping expertise of contributors from many relevant disciplines, especially healthcare management professionals. This edition offers new or expanded coverage of healthcare reform; quality initiatives; Magnet-certified hospitals; emotional and multicratic leadership; social media; preparation for large-scale emergencies; prevention and response to bullying and workplace violence; and much more. Throughout, new MediaLink boxes link readers to updated resources and activities on the web.

  • Sales Rank: #25330 in Books
  • Brand: Brand: Prentice Hall
  • Published on: 2012-08-05
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.90" h x .70" w x 7.90" l, 1.35 pounds
  • Binding: Paperback
  • 368 pages
Features
  • Used Book in Good Condition

From the Author
Want an informative guide to management? How to handle difficult situations? Create a future as a leader? Effective Leadership and Management does all this and more!

From the Inside Flap
Everything you need to know to become a successful leader is found in the book's four sections. 
     1. Understanding Nursing Management and Organizations  
     2. Learning Key Skills in Nursing Management
     3. Managing Resources
     4. Taking Care of Yourself

From the Back Cover
Online student resources are included with this textbook: nursing.pearsonhighered.com

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Very informative
By susan ainsworth
very informative book. Reading flows well. Good reference book. Will hold onto it after my class is complete for further reference.

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Great resource.
By FNN
This is a great book for beginners in any leadership position or simply for anyone new to the professional world.

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Thursday, October 11, 2012

[C469.Ebook] Ebook Download Sacred Monsters: Mysterious and Mythical Creatures of Scripture, Talmud and Midrash, by Natan Slifkin

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Sacred Monsters: Mysterious and Mythical Creatures of Scripture, Talmud and Midrash, by Natan Slifkin

Unicorns, mermaids, dragons, and phoenixes may feel at home in fantasy literature, but references to these and other mysterious creatures go back much further in history. The Bible, Talmud, and Midrash refer to many such strange creatures. In this beautifully designed and richly illustrated book, Natan Slifkin, the famed "zoo rabbi" and author of Seasons of Life, Nature's Song, and The Challenge of Creation, examines a host of mythic and not so mythic creatures from both their Torah descriptions and modern zoological research, giving us a new perspective on the interface between science, myth, and Torah thought. Greatly expanding on a prior book, Mysterious Creatures, Rabbi Slifkin explores conflicts between the Talmud and science in the context of Torah mysteries of zoology. The Talmud and Midrash discuss a wide range of bizarre creatures, including mermaids, unicorns, griffins, dragons, sea-serpents and phoenixes, as well as strange biological concepts such as spontaneous generation. Sacred Monsters discusses these cases in detail and brings a range of different approaches for understanding them. It is an essential book for any student or educator who has ever struggled with conflicts between the Talmud and science. Strikingly designed, and including extraordinary photographs and illustrations, this is a truly stimulating work. The goal of this book is not merely to persuade readers that the Talmud and Midrash are worthy of their interest. It is important to discuss these creatures for the same reason that the Sages of the Talmud and Torah scholars throughout the ages saw fit to discuss them &emdash; namely, that they are also part of Torah. Torah is not just about history, religious ritual and laws of interpersonal conduct. It is an extremely broad field of study that encompasses many different topics. Some areas of the Torah are more popular or more relevant than others, but we should not neglect the others. The animals of this book are discussed in classical Jewish literature for a variety of reasons. With some, such as the tachash, it is a matter of understanding the construction of the Tabernacle. With others, such as the mermaid, the goal is to clarify a matter of law. And with yet others, such as Leviathan, the point is to convey various theological messages. Furthermore, there is a particular pressing need for a book of this nature. When people encounter references to such creatures in the Talmud, they can be left with anything from gnawing questions to a severe crisis of faith. Did such creatures really exist? Did the Sages of the Talmud really believe in such creatures? What are we to make of it? This book studies the history of the various approaches that have traditionally been taken by Torah scholars in resolving such issues.

  • Sales Rank: #4834515 in Books
  • Published on: 2007-09-03
  • Original language: English
  • Dimensions: 9.50" h x 6.75" w x 1.25" l, 1.65 pounds
  • Binding: Hardcover
  • 384 pages

Review
Rabbi Natan Slifkin's new book, Sacred Monsters, is a very impressive work, combining exceptionally broad scholarship in such varied fields as science, classical literature, and the Jewish tradition. It provides fascinating insights into the literature of legendary creatures and their possible origins. In this particular book, the author has managed to avoid the many pitfalls awaiting anyone treating the intersection between science and Torah. --Professor Yehudah Leo Levi, Rector Emeritus, Jerusalem College of Technology, Author, Torah and Science

Rabbi Natan Slifkin's newest book is a delightful mix of Talmudic teachings, zoological science, and historical investigations. Anyone who ever doubted the comprehensiveness of our Torah will now be convinced that kulah bah -- there is a place in it even for 'sacred monsters.' Rabbi Slifkin is to be commended for once again offering us a work which answers questions, informs, and, in this case, even entertains. --Rabbi Dr. Tzvi Hersh Weinreb, Executive Vice President, The Orthodox Union

References in the Talmud and Midrash to curious zoological phenomena are often more mystifying than the creatures themselves. Rabbi Slifkin's thorough scholarship, so well proven in his previous works, comes through once again. Even more important than providing answers to thorny questions surrounding the subjects of the book's title, this work helps the student plot a steady course through the sometimes churning waters of the Sages' science. How much did they rely on the science of their day? When did they--and when did they not--mean to be taken literally? Rabbi Slifkin provides answers consistent with the spirit of our mesorah. By doing so, the profundity of the Torah of our Sages shines with even greater brilliance. --Rabbi Yitzchok Adlerstein, Author, Maharal: Be'er HaGolah

References in the Talmud and Midrash to curious zoological phenomena are often more mystifying than the creatures themselves. Rabbi Slifkin's thorough scholarship, so well proven in his previous works, comes through once again. Even more important than providing answers to thorny questions surrounding the subjects of the book's title, this work helps the student plot a steady course through the sometimes churning waters of the Sages' science. How much did they rely on the science of their day? When did they--and when did they not--mean to be taken literally? Rabbi Slifkin provides answers consistent with the spirit of our mesorah. By doing so, the profundity of the Torah of our Sages shines with even greater brilliance. --Rabbi Yitzchok Adlerstein, Author, Maharal: Be'er HaGolah

Rabbi Natan Slifkin's new book, Sacred Monsters, is a very impressive work, combining exceptionally broad scholarship in such varied fields as science, classical literature, and the Jewish tradition. It provides fascinating insights into the literature of legendary creatures and their possible origins. In this particular book, the author has managed to avoid the many pitfalls awaiting anyone treating the intersection between science and Torah. --Professor Yehudah Leo Levi, Rector Emeritus, Jerusalem College of Technology, Author, Torah and Science

About the Author
Born in Manchester, England, Rabbi Natan Slifkin studied there at Yeshivas Shaarei Torah. He then moved to Israel, where he spent many years in study, at Yeshivas Midrash Shmuel and the Mir Yeshivah. He then taught Talmud and Jewish philosophy at Ohr Somayach Institutions, where he received ordination, and now teaches an extensive Zoo Torah course at Yeshivat Lev HaTorah and Midreshet Moriah Seminary for Women. Rabbi Slifkin has written extensively for the Daf Yomi Advancement Forum and many newspapers, websites and journals. He has been invited as guest lecturer to Bar Ilan University and to numerous synagogues worldwide. Several years ago, Rabbi Slifkin began teaching about the relationship between Judaism and the animal kingdom at the Jerusalem Biblical Zoo. He then developed the Zoo Torah program, which he has since successfully operated in New York, Detroit, Philadelphia, Washington D.C., Baltimore, St. Louis, Atlanta, Phoenix, Los Angeles, and San Diego. This program has led Rabbi Slifkin to be featured in television and radio shows as well as in countless newspapers and journals. Rabbi Slifkin has a lifelong fascination with wildlife and has kept a wide variety of exotic pets, including iguanas and tarantulas! His studies of wildlife have led him hiking extensively in Israel, scuba diving to coral reefs in Eilat, on safari in Kenya, whale-watching in California, and behind the scenes at numerous zoological facilities worldwide.

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5 of 5 people found the following review helpful.
Science Fiction in the Talmud?
By Dr Dave
As the only scientist at most Talmud sessions I am usually put on the spot as being sacriligious for not accepting the fundamentalist approach. Rabbi Slifkin has calmed and comforted me by gathering pertinent alternative explanations from Jewish source texts. If I were learned enough I would have liked to have written this and some other of his books.

3 of 3 people found the following review helpful.
wonderful book
By zochnas
A wonderful book. Respectful of rabbinic authority and knowlegeable, the author has an inciteful and extensive knowlege of history, halacha and Torah. His approach to resolving issues concerning science, the modern world and Torah is surely going to result in his being acclaimed in future as one of the gedolim of our age.

2 of 2 people found the following review helpful.
Great Book.
By S. Dzh
its an amazing read. Got lucky that I have a copy, got it signed as well. (Should have brought more copies when had the chance for $25/each) It's a bummer that this book isn't re-printed and copies are low.
This book analyzes creatures and phenomena both from a scientific and Jewish point of view, bringing sources upon sources for the material. Also asking what was meant and understood literal and what was not. And also bringing down the deeper meanings of questions like giants for example and what the measurements symbolize. Over-all great book.

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Sacred Monsters: Mysterious and Mythical Creatures of Scripture, Talmud and Midrash, by Natan Slifkin PDF
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Tuesday, October 2, 2012

[T727.Ebook] Free Ebook The Lean-To and It's Variants Used in Survival and Bush Bough Beds, by Mors Kochanski

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The Lean-To and It's Variants Used in Survival and Bush Bough Beds, by Mors Kochanski

Open Fronted Lean-to Principles, The Simple Open-Fronted Lean-to, Thermal Mass Version, Insulation Version, The Open-Fronted Lean-to Made of Flexible Materials, More Than One Occupant, Bough Beds, The Simple Bed, The Standard Mat, The Deluxe Bed, Larger Beds, Making a Winter Snow-Based Bed are all covered.

  • Sales Rank: #303952 in eBooks
  • Published on: 2013-12-01
  • Released on: 2013-12-01
  • Format: Kindle eBook

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3 of 3 people found the following review helpful.
For the price ($2 on Kindle) this is a good product. It is relatively short but hits on ...
By Kendig Bergstresser
For the price ($2 on Kindle) this is a good product. It is relatively short but hits on the key principles of building a lean-to shelter. The author seems to have a lot of practical experience in this area. This is a short read and is more of a long pamphlet than a full length book, but it is worth the read and good to keep as guide. I have read other survival books and while they cover making a lean-to, this is probably one of the most comprehensive readings on the topic. The author does call out teepees and other variations of lean-to's but does not go into any real detail there. In some respects I was hoping for more, where he would get into advanced types of lean-tos, but this covers more of the basic variety - but it does it quite well!

3 of 3 people found the following review helpful.
Grayfox like'm book
By Richard Kranz
Great book. It's got very easy to understand, & do. Get for Old'str & Your'str
That's a book should be!

3 of 3 people found the following review helpful.
Four Stars
By Ken Szakacsi
Very good book for the bush

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[K350.Ebook] Download Ebook Gauge Theory of Weak Interactions, by Berndt Muller Walter Greiner

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  • Published on: 1996
  • Binding: Hardcover

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Monday, October 1, 2012

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  • Published on: 1995-11-30
  • Binding: Hardcover

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